I have been having Crohn's Disease for the past fifteen years. I have a severe case. Do you know of any new treatemts? I take Asacol, 180 pills per month, Purinethol 50 mg, one per day. Lomotil, as needed. I also have osteoperosis and I take Actonel 150 mg., one per month. I take Zoloft 100 mg., one per day, and Fioricet for my headaches, as needed. Please advise. I got the Osteoperosis because I was on high dose steroids for nine months. I was on 80 mg. per day